![]() drug withdrawal – symptoms that occur upon cessation of repeated drug use.drug sensitization or reverse tolerance – the escalating effect of a drug resulting from repeated administration at a given dose.dependence – an adaptive state associated with a withdrawal syndrome upon cessation of repeated exposure to a stimulus (e.g., drug intake).addictive drug – psychoactive substances that with repeated use are associated with significantly higher rates of substance use disorders, due in large part to the drug's effect on brain reward systems. ![]() addiction – a biopsychosocial disorder characterized by persistent use of drugs (including alcohol) despite substantial harm and adverse consequences.Psychiatry, clinical psychology, toxicology, addiction medicineĪddiction and dependence glossary Brain positron emission tomography images that compare brain metabolism in a healthy individual and an individual with a cocaine addiction
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